When a poison taster becomes accidentally important at work, multiple seasons of a blockbuster anime follow, and she cannot help it. Based on Natsu Hyūga's novels, Maomao's tale of mystery, medicine, and a master full of secrets finds global popularity, as The Apothecary Diaries continues to fuel anticipation, now with Season 3 officially announced. With its multi-layered plotting and a heroine juggling ambition and alchemy, the series hums with unspoken menace, exactly the kind of story to propel late-night binges.

Now is a great time to catch up on the initial two seasons of the anime before the highly anticipated third arrives, so as not to feel left out. 

In the US, The Apothecary Diaries is available to stream on Crunchyroll, which is streaming the anime internationally outside of Asia. As of early 2025, Season 1 (24 episodes) became available on Netflix US. But its catalog does not contain Season 2 yet, though Netflix streams the second part in some Asian regions. Crunchyroll is distributing both seasons globally, and within the US, the anime is also available on Hulu and can be rented on Apple TV or Amazon Video.

The Apothecary Diaries is streaming on Crunchyroll for free with ads in the US, and also without ads for $7.99 per month, available in English, Portuguese, Italian, German, Spanish, French, and other languages. The growing popularity of the anime and positive fan response have fueled a hunger for its upcoming third season. Though Netflix's first season provided the show with renewed exposure and the potential to reach more audiences, Crunchyroll is highly likely to take the charge forward for the buzzing next season.

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Whether one is ahead of the curve as an avid reader of The Apothecary Diaries light novel series or just patiently waiting for the anime, audiences are in for a great surprise with what is to come.

The Apothecary Diaries announced on October 22, 2025, that Season 3 is indeed under production. The upcoming season is set to release in October 2026 in the form of a split two-part release; the second half is scheduled for April 2027. As part of the Series 3 announcement, a theatrical movie with an original story from author Natsu Hyūga connected to the anime was also announced due in December 2026. Though streaming information for the upcoming season has not been revealed yet, with Crunchyroll and Netflix's staggering global success with anime, viewers can rest assured of its availability soon. 

Based on production information, Season 3 will likely see Maomao stepping outside of the palace gates into larger political and supernatural enigmas, battling plagues and secrets. This season could be adapting Volumes 4 and 5 of the light novels, shipping Maomao and Jinshi to Empress Gyokuyou’s homeland. Anticipation intensifies the stakes as palace politics, a potential national-scale danger, and fresh characters with great abs take center stage. Meanwhile, Seasons 1 and 2 are already live on Crunchyroll to help viewers buckle up for impending poison chaos.

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Have you watched The Apothecary Diaries yet? Comment your thoughts below.